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3D BRAIN MODELING

Advancing the technology

We tackle ongoing challenges in brain organoid models. For instance, we are interested in efficient vascularization in brain organoids, which is the prerequisite for their long-term maturation and functional refinement. We pursue this through various techniques of stem cell biology and neurobiology.

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HUMAN BRAIN DEVELOPMENT

Physiological and Etiological Development

We apply brain organoids to understand human brain development. Basing on fused brain organoids recapitulating regional interactions within the human brain, we now can track interneuron migration and axonal projection in a dish. With that, new mechanistic insights at the molecular level can be gained to better understand human neurodevelopmental disorders.