Selected Publications

*First Author, # Corresponding Author

Selected Publications
*First Author
#Corresponding Author

Barral, Serena#*; Xiang, Yangfei#; Birey, Fikri#.Improving in vitro modeling of human brain with future brain organoids.FRONTIERS IN MOLECULAR NEUROSCIENCE. 09 Aug 2022. 15.

 

Bilal Cakir; Yoshiaki Tanaka ; Ferdi Ridvan Kiral ; Yangfei Xiang; Onur Dagliyan; Juan Wang ; Maria Lee; Allison M Greaney; Woo Sub Yang; Catherine duBoulay ; Mehmet Hamdi Kural ; Benjamin Patterson; Mei Zhong; Jonghun Kim ; Yalai Bai ; Wang Min ; Laura E Niklason ; Prabir Patra ; In-Hyun Park#.Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids.NAT COMMUN. Jan 2022. 13(1):430.

Lu, Xiaoxiang*; Yang, Jiajie; Xiang, Yangfei#.Modeling human neurodevelopmental diseases with brain organoids.CELL REGENERATION. 01 Dec 2022. 11(1).

Tikhonova, Anastasia#*; Xiang, Yangfei#*; Gifford, Casey#*.Early-career researchers in the time of COVID-19: Starting a new lab during a pandemic.CELL STEM CELL. 2021 May 6;28(5):808-810.

Smith, Quinton#*; McKinley, Kara L.#*; Chan, Chii Jou#*; Sikandar, Shaheen#*; Xiang, Yangfei#*; Passaro, Diana#*.Introductions to the Community: Early-Career Researchers in the Time of COVID-19.CELL STEM CELL. Nov 2020. 27(5):702-704.

Xiang, Yangfei*; Tanaka, Yoshiaki; Patterson, Benjamin; Hwang, Sung-Min; Hysolli, Eriona; Cakir, Bilal; Kim, Kun-Yong; Wang, Wanshan; Kang, Young-Jin; Clement, Ethan M.; Zhong, Mei; Lee, Sang-Hun; Cho, Yee Sook; Patra, Prabir; Sullivan, Gareth J.; Weissman, Sherman M.; Park, In-Hyun#.Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons.MOLECULAR CELL. 2020. 79(1):84-+.

Yangfei Xiang#*; Bilal Cakir; In-Hyun Park#.Deconstructing and Reconstructing the Human Brain With Regionally Specified Brain Organoids.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2020.

Yoshiaki Tanaka*; Bilal Cakir; Yangfei Xiang; Gareth J. Sullivan; In-Hyun Park#.Synthetic Analyses of Single-Cell Transcriptomes From Multiple Brain Organoids and Fetal Brain.CELL REPORTS. 2020. 30(6):1682-1689.

Cakir, Bilal*; Xiang, Yangfei*; Tanaka, Yoshiaki; Kural, Mehmet H.; Parent, Maxime; Kang, Young-Jin; Chapeton, Kayley; Patterson, Benjamin; Yuan, Yifan; He, Chang-Shun; Raredon, Micha Sam B.; Dengelegi, Jake; Kim, Kun-Yong; Sun, Pingnan; Zhong, Mei; Lee, Sangho; Patra, Prabir; Hyder, Fahmeed; Niklason, Laura E.; Lee, Sang-Hun; Yoon, Young-Sup; Park, In-Hyun#.Engineering of human brain organoids with a functional vascular-like system.NATURE METHODS. 2019. 16(11):1169.

Xiang, Yangfei#*; Bilal Cakir; In-Hyun Park.Generation of regionally specified human brain organoids resembling thalamus development.CELL PRESS: STAR PROTOCOLS. 2019.

Xiang, Yangfei*; Tanaka, Yoshiaki*; Cakir, Bilal; Patterson, Benjamin; Kim, Kun-Yong; Sun, Pingnan; Kang, Young-Jin; Zhong, Mei; Liu, Xinran; Patra, Prabir; Lee, Sang-Hun; Weissman, Sherman M.; Park, In-Hyun#.hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids.CELL STEM CELL. 2019. 24(3):487.

Xiang, Yangfei*; Tanaka Yoshiaki; Benjamin Patterson; Bilal Cakir; Kun-Yong Kim; Yee Sook Cho; In-Hyun Park#.Generation and fusion of human cortical and medial ganglionic eminence brain organoids.CURRENT PROTOCOLS IN STEM CELL BIOLOGY. 2018.

Kim, Kun-Yong*; Tanaka, Yoshiaki; Su, Juan; Cakir, Bilal; Xiang, Yangfei; Patterson, Benjamin; Ding, Junjun; Jung, Yong-Wook; Kim, Ji-Hyun; Hysolli, Eriona; Lee, Haelim; Dajani, Rana; Kim, Jonghwan; Zhong, Mei; Lee, Jeong-Heon; Skalnik, David; Lim, Jeong Mook; Sullivan, Gareth J.; Wang, Jianlong; Park, In-Hyun#.Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a.NATURE COMMUNICATIONS. 2018. 9.

Xiang, Yangfei*; Tanaka, Yoshiaki*; Patterson, Benjamin; Kang, Young-Jin; Govindaiah, Gubbi; Roselaar, Naomi; Cakir, Bilal; Kim, Kun-Yong; Lombroso, Adam P.; Hwang, Sung-Min; Zhong, Mei; Stanley, Edouard G.; Elefanty, Andrew G.; Naegele, Janice R.; Lee, Sang-Hun; Weissman, Sherman M.; Park, In-Hyun#.Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration.CELL STEM CELL. 2017. 21(3):383.

Teaching

Graduate course: Principles of Regenerative Medicine (Spring)

Undergrad course: Brain Organoids (Fall)

Undergrad course: Fundamentals of Biomedical Engineering (Fall)

Graduate course: Experimental Biology (Fall) ​